Summer school in Nutritional Metabolomics – ​1st – 5th ​October 2018.

October 1st

15.00 – 16.00 Registration

16.00 – 16.15 Openings: Prof. Pierluigi Caboni – Prof. Luigi Atzori, University of Cagliari, Italy

16.15 – 17.15 Plenary lecture – Metabolomics and the Dream of Precision Nutrition – Prof. David Wishart, University of Alberta, Canada

17.15 – 18.30 Welcome cocktail at Sardegna ricerche

October 2nd

9.00 – 9.45 Lecture – Metabolomics and Dietary Biomarkers –  Prof. Lorraine Brennan, Institute of Food and Health and Conway Institute, UCD School of Agriculture and Food Science, Dublin, Ireland.

9.45-10.30 Lecture – Analytical trends in Human Nutrition – Dr. Serge Rezzi, Nestlé Institute of Health Sciences, Lausanne, Switzerland

10.30 – 11.00  Lecture – MS based metabolomics: an introduction Mass spectrometry – Prof. Pietro Franceschi, Fondazione Edmund Mach (TN) Italy

11.00 – 11.30 Coffee break

11.30 – 12.00 Lecture – Data Analysis Strategies – Prof. Marina Cocchi, Università degli Studi di Modena e Reggio Emilia, Italy

12.00 – 12.30 Lecture – Data analysis: PLS in metabolomics –  Prof. Matteo Stocchero, University of Padua, Italy

12.30 – 12.45 Introduction to hands on activity – Dr. Marynka Ulaszewska, Fondazione Edmund Mach (TN), Italy

12.45 – 13.00 Introduction to hands on activity NMR spectroscopy experiments in metabolomics – Dr. Cristina Piras, University of Cagliari, Italy

13 – 14.15 Lunch

14.30 – 16.00 Tutorial activity – Annotations from A to Z: theory and practice for LC-MS based metabolomics (Bring with you spectra you wish to annotate!!) – Dr. Marynka Ulaszewska, Fondazione Edmund Mach (TN), Italy

16.00 -17.30 Tutorial activity – part 1 – NMR spectroscopy experiments in metabolomics – Dr. Cristina Piras, Department of Biomedical Sciences, Oncology and Molecular Pathology Unit, University of Cagliari, Italy

October 3rd

9.00 – 9.45 Lecture – Nutritional metabolomics and the study of dietary patterns in Clinical & Epidemiological studies: beyond the Mediterranean Diet – Prof. Cristina Andres-Lacueva, Nutrition, Food Science & Gastronomy Department, University of Barcelona, Spain. CIBER of Frailty and Healthy Aging (CIBERFES)

9.45 – 10.30 Lecture – Precision Nutrition- the role for metabolomics –  Prof. Lorraine Brennan – Institute of Food and Health and Conway Institute, UCD School of Agriculture and Food Science, Dublin, Ireland

10.30 – 11.00 Lecture – Overview of International data standards and repository – Prof. Reza Salek, International Agency for Research on Cancer, WHO, France

11.00 – 11.30 Coffee break

11.30 – 12.15 Lecture – Biomarker classification and validation from a metabolomics perspective – Prof. Lars Ove Dragsted, University of Copenhagen, Denmark

12.15 – 13.00 Lecture –  Ion Mobility for Untargeted Lipidomics – Dr. Andrea Armirotti, IIT Genova, Italy

13 – 14.15 Lunch

14.30 – 16.00 Tutorial activity – part 2 – NMR spectroscopy in metabolomics application – Prof. Paola Scano, Department of Chemical and Geological Sciences, University of Cagliari, Italy

16.00 -17.30 Tutorial activity – Mass spectrometry – Mass Spectrometry strategies for advanced lipid profiling – Dr. Hector Gallart Ayala, UNIL Metabolomics University of Lausanne, Switzerland

October 4th

9.00 – 9.45 Lecture – Odd sample types and multiple profiling – Prof. Lars Ove Dragsted, University of Copenhagen, Denmark

9.45 – 10.30 Lecture – In silico Metabolomics and Novel Compound Identification in Nutrition Studies – Prof. David Wishart, University of Alberta, Canada.

10.30 – 11.00 Lecture –  Pre-analytical factors and their influence on analytical quality in nutrimetabolomics – Dr. Marynka Ulaszewska, Fondazione Edmund Mach (TN), Italy

11.00 – 11.30 Coffee break

11.30 – 12.15 Lecture – Workflow for metabolomics data and pathway analysis using XCMS Online – Prof. Julijana Ivanisevic, UNIL Metabolomics University of Lausanne, Switzerland

12.15 – 12.45 Lecture – Do these Branch Chain Amino Acids make my bum look big? And other stories from metabolomics and human intervention studies – Prof. Jules Griffin, University of Cambridge, U.K.

13 – 14.15 Lunch

14.30 – 16.00 Tutorial activity – Projection to latent structures with orthogonal constraints: structured noise and data fusion – Prof. Matteo Stocchero, University of Padua, Italy

20.00 Social dinner at Bacchixeddu Restaurant (Pula)

October 5th

9.00 – 9.30 Lecture – Beyond biomarkers and towards mechanisms – Prof. Julijana Ivanisevic – UNIL Metabolomics University of Lausanne, Switzwerland

9.30 – 10.00 Lecture – Exposome and Cancer metabolomics – Prof. Reza Salek, International Agency for Research on Cancer, WHO, France

10.00 – 10.30 Lecture  – Metabolomics in complex experimental designs. Are we ready for that? – Prof. Pietro Franceschi, Fondazione Edmund Mach (TN), Italy

11.00 – 11.30 Coffee break

11.00 – 11.30 Lecture  – What to measure in metabolomics? – Prof. Luigi Atzori Department of Biomedical Sciences, Oncology and Molecular Pathology Unit, University of Cagliari, Italy

11.30 – 12.00 Lecture  – Iodine deficiency during pregnancy – Prof. Pierluigi Caboni, Department of Life and Environmental Sciences, High Resolution Mass Spectrometry Laboratory, Food Toxicology Unit, University of Cagliari, Italy

12.00 – 12.30 – Conclusions

13 – 14 Lunch